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The GLP-1 pathway's effectiveness depends partly on how efficiently your body's GLP1R gene variant processes the medicationa key reason PlexusDx offers the Precision Peptide Genetic Test to map your peptide metabolism across 14 pathways

"The physiology of IGF-1 in hypertrophy." J Gerontol Med Sci.

Another limitation is the short duration of most trials

That sort of prompted my dive into the literature. JAMA Medical News While more RCTs for GLP-1s and addiction are needed and underway, we believe there is already substantial evidence that these drugs are effective in reducing addictive drive for a large percentage of patients